• A device that augments heartbeats

    The traditional image of the heart’s pumping function is that is squeezes the blood out into the circulatory system. New research has shown that the mitral valve, which is to prevent the blood from flowing back from the left ventricle…

    • Project name: New product and method for the treatment of heart failure patients
    • Project category: Med Tech
    • Sjukdomsområde:
    • Regional tillhörighet: South Sweden
  • How blood-free analysis could become a reality

    “Many people have tried to create a way for diabetics to measure their glucose levels without pricking a finger to draw blood. Currently, most patients with type 1 diabetes are forced to measure their blood sugar levels by pricking themselves…

    • Project name: Verification of the sensor principle in a product for glucose measurement
    • Project category: Diagnostics
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: East Middle Sweden
  • The movements of the cells reveal the risk of metastasis

    He is a stem cell researcher and cell biologist at Karolinska Institutet who is managing the Cellrace research project together with Liv Diagnostics, with the aim of developing a new, powerful tool to support diagnostics in cancer care. Nanosurface imitates…

    • Project name: Cellrace – a tool for advanced cancer diagnosis
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: Stockholm
  • Sensors integrate human and machine

    This is the assessment of Max Ortiz Catalan, associate professor of medical engineering at Chalmers University of Technology in Gothenburg. The development work, in which Swelife is funding the mechanical tests of the attachment of a new bone prosthesis, is…

    • Project name: Neurally-controlled prosthetic leg
    • Project category: Med Tech
    • Sjukdomsområde: Other
    • Regional tillhörighet: West Sweden
  • Remaining islet cells can be saved

    MSCs have properties that contribute to preventing further destruction of so-called islet cells, which is helpful in case of type 1 diabetes. The effect has been proven and a couple of challenges remain, besides proving the effect in larger patient…

    • Project name: Development of mesenchymal stem cells into an effective treatment for patients with type 1 diabetes
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: Stockholm
  • Genomic Medicine Sweden GMS

    Unique molecule opens up potential new cancer treatment

    Cisplatin has been used since the late 1970s in chemotherapy for many types of cancer. The treatment causes DNA damage in the cancer cells and is often effective. “In many cases, however, the patient responds progressively worse to the treatment…

    • Project name: New treatment for cisplatin-resistant cancer with OGG1 inhibitors
    • Project category: Medicine
    • Sjukdomsområde: CancerOther
    • Regional tillhörighet: Stockholm
  • Mapping the way to faster cancer diagnosis

    “We now have a prototype of the instrument capable of generating this map, which can be compared to a topographical image with variations in ´altitude’ that correspond to the degree of stiffness in the tissue sample. We also have a…

    • Project name: Instrument and method for future diagnostics in pathology
    • Project category: Med Tech
    • Sjukdomsområde: CancerOther
    • Regional tillhörighet: North Sweden
  • An asthma-checking app is on the way

    So says Anna Carleborg, research nurse at Karolinska Institutet, who is conducting a study to evaluate the tool on patients and healthcare staff. The app is called Asthmatuner Diagnosis and was developed by a team led by Henrik Ljungberg and…

    • Project name: A time-saving diagnostic tool for asthma and other pulmonary diseases
    • Project category: DiagnosticsE-health/M-healthMed Tech
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • How to save lives and the eyesight of premature infants

    “Too much oxygen causes severe eye damage, too little increases the risk of brain injury and death”, says Kenneth Danehorn, Master of Engineering in technical physics and electrotechnology at the Institute of Technology at Linköping University. There is an optimal…

    • Project name: System for monitoring oxygen treatment in neonatal care
    • Project category: Med Tech
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • Rapid analysis is the new weapon in the fight

    Rapid share is the name of the technology, developed by 1928 Diagnostics in Gothenburg. In one go, it solves two very difficult challenges: it analyses the complete genome from isolated bacteria and allows hospitals to share the information with each…

    • Project name: Rapid share – real time infection tracking to limit the spread of antibiotic-resistant bacteria
    • Project category: Diagnostics
    • Sjukdomsområde: InfectiousOther
    • Regional tillhörighet: West Sweden
  • One breath detects lung cancer at an early stage

    Lung cancer, one of the most common cancers, is also one of those that has the worst prognosis. When a lung tumour has been diagnosed, it has often grown to such a size that it cannot be treated effectively. To…

    • Project name: Method of screening for COPD and lung cancer
    • Project category: Diagnostics
    • Sjukdomsområde: CancerOther
    • Regional tillhörighet: Stockholm
  • A pharmaceutical that inhibits the spread of cancer

    Kancera’s HDAC6 project was based on earlier studies of a variant of the enzyme called HDAC6. Researchers connected with the company have previously shown that when HDAC6 is inhibited, the immunosuppression effect of tumours is reduced. The project encompasses collaboration…

    • Project name: Development of an anti-cancer pharmaceutical candidate with a unique mechanism
    • Project category: Medicine
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: Stockholm
  • New pharmaceutical candidate prevents inflammation and thrombosis formation

    “Renaparin heals the vessel damage that otherwise means the body does not accept the new organ in a good way”, says Peetra Magnusson, head of the research project. An ischemic process starts as soon as an organ is removed from…

    • Project name: Renaparin to improve kidney transplantation for patients with chronic kidney disease
    • Project category: Medicine
    • Sjukdomsområde: Other
    • Regional tillhörighet: East Middle Sweden
  • New markers for tailored treatment

    Roland Andersson, professor of surgery at Skåne University Hospital, is on the way to answering these questions. Together with his team, he is progressing towards a new test for pancreatic tumours. “There has been no breakthrough on these points, but…

    • Project name: Development of a new diagnostic and prognostic biomarker panel in blood for pancreatic cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: South Sweden
  • Type 2 diabetes is five different conditions

    “We have developed an analysis method that separates the different groups from each other. Hopefully, they can identify pre-diabetic people in order to provide prevention and early treatment.” 85–90 per cent of those with diabetes have type 2 “For 100…

    • Project name: Development of a new diagnostic tool for individualised diabetes treatment
    • Project category: Diagnostics
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: South Sweden
  • How islet cells can survive – and save lives

    A sub-group of patients with type 1 diabetes have a very severe form of the disease. Fluctuations in blood sugar arise very rapidly and are almost impossible to control. Quality of life is adversely affected and there is a high…

    • Project name: Clinical study for improved treatment of type 1 diabetes
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: East Middle Sweden
  • The molecule that stops eczema itching

    “It’s a vicious circle. The more you scratch yourself, the more the immune system is triggered and then the itching gets even worse. Our patented molecule relieves the itching and that is a considerable benefit”, says Anna-Lena Spetz, professor of…

    • Project name: Development of MedON for atopic dermatitis
    • Project category: Medicine
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • Timely detection of the second-most deadly form of cancer

    “Once the pancreatic cancer produces symptoms as it reaches the later stages, it is usually no longer operable. There is no medicinal cure and the patient usually dies within a few months”, says Ulrika Axelsson, PhD. She is coordinating a…

    • Project name: Test for early diagnosis of pancreatic cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: South Sweden
  • Blood test can save lives and reduce suffering

    One in six women at some point seeks medical attention for pelvic pain, with symptoms for which surgery is performed, following an ultrasound, to check whether it is cancer of the uterus, ovaries or lining of the uterous. In the…

    • Project name: Biomarker test for cervical, ovarian and endometrial cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: East Middle Sweden
  • Unique substance may help half a billion diabetes patients

    Type 2 diabetes is a disease that is increasing almost epidemically worldwide. Out the 426 million people currently diagnosed with diabetes, 90–95 per cent have diabetes type 2. Furthermore, it is estimated that many more suffer from the disease without…

    • Project name: A revolutionary way to combat type 2 diabetes, independent of the insulin pathway
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: Stockholm
  • Innovation offers hope of relief

    There are two variants of the herpes simplex virus. HSV 1 causes oral herpes, which is very common and contracted during childhood. The genital variant, HSV 2, causes symptoms in the form of painful blisters and sores on and around…

    • Project name: Development of a therapeutic vaccine against genital herpes simplex virus 2 infection
    • Project category: Medicine
    • Sjukdomsområde: Infectious
    • Regional tillhörighet: West Sweden
  • Smart app provides prognoses and information

    The solution is an app that can predict dangerously high or low blood sugar levels, and that is currently heading for clinical testing and commercialisation. The app developed by Fredrik Ståhl communicates with a sensor of the same type as…

    • Project name: Personalised decision support for insulin-treated diabetes
    • Project category: E-health/M-health
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: South Sweden
  • Sharp detailed image provides opportunity for personalised treatment

    “With our patented analysis method, AMLC, a large number of cell markers can be visualised simultaneously within the same tissue section. Qualitatively, it means that we can obtain much more detailed information from a single tissue sample. Quantitatively, it allows…

    • Project name: AMLC – A novel method for advanced in vitro diagnostics of cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: South Sweden
  • New foods can prevent diabetes and obesity

    Those who eat fibres derived from barley experience better regulation of both blood sugar level and appetite than otherwise – up to 16 hours after the meal. This has been established by Anne Nilsson and her research colleagues at the…

    • Project name: Validation of new antidiabetic food concept based on modulation of intestinal flora 
    • Project category: Others
    • Sjukdomsområde: DiabetesOther
    • Regional tillhörighet: South Sweden
  • AI improving diagnosis of prostate cancer

    Prostate cancer is the most common form of cancer in men. In Sweden, around 10 000 men are struck down each year. When a pathologist makes a diagnosis using a microscope, there is also an assessment of the cancer cells’…

    • Project name: DOGS – Computerised image analysis for rapid and exact diagnosis of prostate cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: South Sweden
  • Broccoli is the basis for the research breakthrough

    There is a very great need for new drugs to combat type 2 diabetes. Around 60 million of the 300 million people who currently live with the disease cannot for various reasons (such as high blood pressure and/or diminished kidney…

    • Project name: Sulforaphanoids – new potential antidiabetic drugs
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: South Sweden
  • Enzyme restores balance in the liver

    The new inhibitors she and the team have developed affect the balance between the storage and burning of fat. “The accumulation of fat in the liver is reduced due to the treatment, which restores the metabolic balance in the liver…

    • Project name: New unique medical treatment of type 2 diabetes
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: West Sweden
  • Alzecure: double effect on Alzheimer’s

    Alzheimer’s is a fast-growing disease that causes considerable suffering and is an enormous drain on resources. Globally, one person is struck down every third second and there is still no cure or any way to prevent the disease, which will…

    • Project name: Modulators of Abeta42 synthesis – a new treatment for Alzheimer’s disease
    • Project category: Medicine
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • System biomarker detects cancer in time

    “There is a considerable need for diagnostic methods that can enable us to make a simpler, more exact and more reliable diagnosis of renal cancer”, says Karl Bergman, biotechnician and CEO of Elypta. The main methods currently used are biopsy…

    • Project name: Elypta: System biomarker for detection of renal cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: West Sweden
  • How to avoid unnecessary renal surgery

    “By then, the patient has undergone difficult surgery with anaesthesia, possible side-effects and sick leave. Furthermore, each operation costs the healthcare sector SEK 100 000. With this method, we can avoid that”, says Professor Rimma Axelsson. The major difficulty today…

    • Project name: MIDOR – Molecular Imaging for Differential Diagnosis of Oncocytoma from Renal Carcinoma
    • Project category: Diagnostics
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • Common worm medicine can stop cancer

    “An extensive test had shown that MBZ appears to activate the immune system. I gave it to one of my patients, for whom there were no other treatment options, and after six weeks the tumour had reduced drastically.” Today, there…

    • Project name: Development of small molecule immunomodulating cancer drugs using mebendazole as a model
    • Project category: Medicine
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: East Middle Sweden
  • New test provides more opportunities for proper care

    “Today, less than 1 per cent of the lymph node volume is studied under a microscope. And if tumour cells are found, it is not possible to determine whether or not they are aggressive”, says Lina Olsson. Hiloprobe’s newly developed…

    • Project name: Biomarker test for patients with colorectal cancer
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: North Sweden
  • SAGA develops future standard tests for cancer

    Common methods of diagnosing cancer are usually indirect, slow and may require minor surgery in order to extract tissue samples from suspected tumours which are subsequently examined under the microscope, says Lao Saal, CEO of SAGA Diagnostics and associate professor…

    • Project name: New nanodrop methods for the analysis of circulating tumour DNA in cancer patients
    • Project category: DiagnosticsMed Tech
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: South Sweden
  • A quick test can help millions of allergy sufferers

    “The technology has two crucial benefits. It lets you know how sensitive the patient is to a particular substance, and can be performed on the patient directly, instead of being sent to the lab”, says Anna Nopp. The new test…

    • Project name: Cell-on-chip technology improving allergy diagnostics
    • Project category: DiagnosticsMed Tech
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • Early diagnosis and adapted care for rheumatic patients

    Rheumatoid arthritis (RA) is the most common type rheumatic disease. Close to one per cent of the Swedish population suffer from this autoimmune disease that causes chronic inflammation of the joints. But the course of disease varies greatly from one…

    • Project name: New methods for diagnosis and personalised treatment of rheumatoid arthritis
    • Project category: DiagnosticsE-health/M-health
    • Sjukdomsområde: Other
    • Regional tillhörighet: Stockholm
  • Pelago: The right dosage of the right medication with a new measuring method

    Once fully developed, the patented measuring method, CETSA, can also shorten the time for the development of entirely new drugs. CETSA measures target engagement – how a drug reaches and binds to its target protein – in other words, how…

    • Project name: Validation of diagnostic applications of the CETSA method
    • Project category: Diagnostics
    • Sjukdomsområde: Cancer
    • Regional tillhörighet: Stockholm
  • Sidekick: Health game that triggers our triune brain to make smart choices

    The downside of the growing prosperity is a dramatic increase in what are known as lifestyle diseases, particularly type 2 diabetes. Common complications are stroke and myocardial infarction. In addition to major human suffering, it results in huge healthcare and…

    • Project name: Evidence-based and entertaining tool against type 2 diabetes
    • Project category: E-health/M-health
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: West Sweden
  • New genetically modified bacteria “tricks” the body into healing chronic wounds

    “Lactobacteria produce a protein that makes the body believe that the wound is greater than it actually is and accelerates the healing process”, says Evelina Vågesjö, doctor of physiology and immunology specialist at Uppsala University. The project is currently at…

    • Project name: Biotherapy for faster wound healing in people with diabetes
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: East Middle Sweden
  • Unique carrier provides a more even medication dose

    The discovery of Upsalite was made by Professor Maria Strømme’s research team at Uppsala University and received a lot of media attention in 2013. The material has a very porous structure, where the surface of 1 gram corresponds to a…

    • Project name: Improved treatment of inflammatory bowel disease with the help of mesoporous Upsalite
    • Project category: Medicine
    • Sjukdomsområde: Other
    • Regional tillhörighet:
  • Apoglyx: New substance provides gentle diabetes medication

    In type 2 diabetes, the body’s glucose control mechanism does not work very well, and many patients instead need to take insulin or other medication to stabilise their blood sugar levels. Normally, the blood sugar level is regulated by reducing…

    • Project name: New therapy against type 2 diabetes
    • Project category: Medicine
    • Sjukdomsområde: Diabetes
    • Regional tillhörighet: South Sweden